Surgery in West Syndrome

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Outcome in West syndrome.

OBJECTIVES To assess the seizure and developmental outcome in children with West syndrome with respect to treatment lag. METHODS Twenty-six children satisfying inclusion criteria of West syndrome i.e., infantile spasms, psychomotor retardation and abnormal EEG pattern were prospectively evaluated. Response to treatment was assessed based on seizure control, EEG, developmental assessment and p...

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Brain connectivity in West syndrome

PURPOSE Hypsarrhythmia, the pathognomonic EEG pattern of West syndrome, is typically characterized by a high amplitude, arrhythmic, and asynchronous pattern. While this severely aberrant pattern would suggest severe abnormalities in connectivity, coherence has not yet been systematically assessed in hypsarrhythmia. METHODS We evaluated the EEGs of 28 infants, 12 with infantile spasms with hyp...

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Wolf–Hirschhorn (4p-) syndrome with West syndrome

Wolf-Hirschhorn syndrome (WHS) is a chromosome disorder (4p-syndrome) which is characterized by craniofacial features and epileptic seizures. Here, we report a case of WHS with West syndrome, in whom the seizures were refractory to several antiepileptic drugs but were responsive to the addition of lamotrigine. The patient had epileptic spasms at age seven months. The interictal electroencephalo...

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West Syndrome: Response to Valproate

UNLABELLED Management of West syndrome is unsatisfactory. In our clinic we observed that a significant proportion of patients respond to usual dose of valproate. OBJECTIVE To prospectively assess the efficacy of valproate in controlling infantile spasms in West syndrome. METHODS Consecutive patients presenting with West syndrome to the Pediatric Neurology Clinic or general outpatient depart...

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Rett's syndrome in the west of Scotland.

Nineteen girls with characteristic features of Rett's syndrome, including normal initial development, regression at about 12 months of age, repetitive hand movements, and severe mental handicap were studied. This represents an estimated incidence of one in 30 000 live births (one in 15 000 girls) in the west of Scotland. Although the children were often initially considered to be autistic, they...

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ژورنال

عنوان ژورنال: Pediatric Neurology Briefs

سال: 1991

ISSN: 2166-6482,1043-3155

DOI: 10.15844/pedneurbriefs-5-10-5